From Professor Robert Melamede, Ph.D. head of the Biology Department at the University of Colorado
The cannabinoid system has existed for about 600 million years ago, it is older than the dinosaurs. The cannabinoid system evolved continuously and all the new species has been taken over. For the "feeds and feeding" the cannabinoid system plays a central role ...
1) cannabinoids are higher in every living animal in front of the stage of polyps and Molluskeln, with the exception of insects. The cannabinoid system keeps the body in homeostatic balance.
2) mothers give their babies a load of cannabinoids in human milk to give them food cravings - so they get the food. (Because they were fed through the umbilical cord, the baby can not)
3) mice without a CB1 cannabinoid receptor may not change. If they are placed in another corner of the cage, encourage them to when they are reset to the old point, they relax - to get excited again when we will implement it. Comment: I wonder if some people, particularly "drug warriors" might also have a blocking CB-1 receptor and oppose so any change - while people like us, enjoy with a unblocked CB-1 receptor, the benefits far relaxed and have no fear of change. An interesting thought - and, amazingly, absolutely correct: The brains of many people are not able to produce good-CB 1 / CB 2 connections.
4) All new species use cannabinoids
5) by her being alive and breathing air our bodies produce free radicals. Cannabinoids help to reverse this.
6) cannabinoids kill brain cells but the cells that will kill them, "glioma", it is the tumor cells in brain cancer. All other brain cells are protected and healed by cannabinoids.
7) Cannabinoids protect against sunburn and skin cancer because of the CB-1 receptors in our skin.
8) Cannabinoids slow down the aging process. Mice whose brains responded to cannabinoids live longer than those in which the CB-1 receptor was blocked.
9) based Activities in the evolutionary advanced areas of the brain cannabinoid receptors and promote higher levels of consciousness.
10) cannabinoids have even been found in white blood cells (CB-2 receptors). These CB-2 receptors were predominantly found in immune cells that regulate the exchange of the immune system in the "Anti-inflammatory" state.
11) cannabinoids protect the heart against Arhytmie
12) your way to help relieve pain relates to the specific nerves of pain transmission. They are called vanilloid receptors. The anandamide, produced naturally by the body of the active ingredient of marijuana, combined with the nerve endings and reduce the pain. Anandamide produced by the body in response to a number of states. For example, aspirin prevents the degradation of anandamide and therefore helps to relieve pain. How many old ladies who say they "never" would consume marijuana, the body's equivalent of no use at all the to know?
13) in most cases, auto-immune diseases of the immune cells of the body produce free radicals that attack your own body as a foreign object. Cannabis brings the immune system in the inflammatory condition and helps to slow the progression of the disease - and thus to prolong life.
14) The active ingredient of marijuana is not only THC, but also from the non-psychoactive cannabidiol (CBD). The mechanism is still not researched exactly clear, however, that cannabis with a high CBD content of the psychoactive "high" THC does nothing.
15) seem to attach to receptors in addition to the higher areas of the brain cannabinoids in many other parts of the body - they act on the skin and many other places.
16) Pharmaceutical companies are working to synthesize different cannabinoid components and new varieties of marijuana. If they are successful, we will have a greater choice of which cannabinoids which areas of the body to use the best.
17) Because of the location of the main receptors CB-1/CB-2 the brain, it seems the natural path of humanity, more "stoned" to be.
18) drug warriors do what they do, not because they are intentionally evil, but rather because they are still primitive ("stupid" one might say). They look with fear and hostility of the world and not cooperative and understanding.
19) According to a study of the brain function of 150 depressed patients cannabis protects healthy cells from dying and protects the nerves.
20) extend cannabinoids bronchial asthma patients and help to breathe. Because of the balance that keeps our body, but it can also provide opportunities, where they act in the opposite, because death is possible if too much is smoked.
21) Cannabinoids control how we see the future. If you are filled with bad experiences, you're afraid of the future. With plenty of cannabinoids on the other hand you want to be in the future. Inability to change from friendly greeting of the future and change.
22) cannabinoids can protect against several types of cancer - they might contribute in the future to heal cancer. They have developed a method to kill the bad cells and good to protect.
23) cannabinoids relieve liver diseases and uncontrollable itching. They work well for insomnia and depression - and that in 600 million years ago.
24) THC in low doses reduces anxiety, while high doses may promote anxiety. Smoking marijuana can reduce anxiety. Taken orally changed, Delta-9-THC on the first pass in the liver of Delta-11-THC, the psychoactive and five times higher for a much longer effect added.
25) Cannabis protects nerve cells from dying and therefore protects against Alzheimer's.
26) head injuries cause increased production of endogenous cannabinoids, which the body protects itself, nor against nerve gas protects the body with cannabinoids. Cannabinoids stimulate the activation of a specific gene to. This is partly on a model organism, a simple worm have been explored. These worms have a very simple nervous system and it turned out that the molecules involved in the so-called "transcription factor" That regulate the genes "turn on". If the expression of this particular gene is activated, the service life of the worms is extended. This we have seen in the mice. Because marijuana "free radicals" destroyed, live people who use cannabis for longer and look younger. Marijuana promotes health through its effect on nerve cells by the immune system in balance and reduces the fat deposits in the cardiovascular system.
27) New research has shown that the argument that cannabis should remain illegal because it "produces cancer," no longer valid added. In the throat, there are nicotine receptors but not cannabinoid receptors. Cells have a biochemical program the "apoptosis" is called, it is activated when cells are damaged too much to repair itself - they commit suicide. This is controlled by biochemical means. However, nicotine activates a path that prevents cells from dying. Something to smoke always brings carcinogens in the respiratory and cardiovascular system. Cells that are destroyed by the smoke will die and we want it to happen, they die before they turn into cancer cells.
28) that cannabinoids reduce pain has long been known. But only recently We also know the molecular mechanisms of pain and the cannabinoid system. We now know that there is overlap between the cannabinoid system and the endogenous opiate system, the endorphins, are - and that they reinforce each other. Thus, people who depend on morphine for pain relief, reduce the dose by 50% if they use cannabinoids.
29) In every system of our body - the nervous system, digestive system, Reproduktionssystm, immune system - cannabinoids are involved in order to maintain what we homeostatic balance - call it - balance. It is a biochemical network that all influenced in our bodies - and also our spirit. But if the whole is always more than the sum of its parts, then what is the big picture of the cannabinoid system? When we see how the cannabinoids diet - digestive - immune system and regulate, what is the effect on the mind? In my opinion, they expand our minds, freeing ourselves of it, tied on a track of thought to be and this is exactly the kind of thinking that we need as we move towards the future, which is always unknown. The cannabinoid system is the ability to adjust to a peaceful and friendly way to change and to be open for it. The cannabinoid system is a holistic Health program. The balance for optimal health is based on the cannabinoid system. Why should cannabis be widely available and used appropriately.
Chanvre.info: chanvre-info.ch/info/de/Info-uber-Cannabinoide.html
At 2004 Cannabis Therapeutics Patentients Out of Time Conference, Dr. Melamede, University of Colorado, explains how the endocannabinoid system functions as a "Global Homeostatic Regulator", balancing several organ systems. He hypothesises that, "Free Radicals are the Friction of Life. Endocannabinoids are the Oil of Life."
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